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RR contributed to the mutation analysis.
SMC contributed to the mutation screening and data analysis and helped to refine the laboratory platform.
FD contributed to the mutation screening and data analysis and helped to refine the laboratory platform.
NR contributed to the mutation screening and data analysis and helped to refine the laboratory platform.
GD contributed to the mutation screening and data analysis and helped to refine the laboratory platform.
GD contributed to the mutation screening and data analysis, helped to refine the laboratory platform, and helped to draft the manuscript.
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These DNA lesions may inevitably contribute to the mutation induction and MN formation.
Exocyclic LPO- derived DNA-lesions are likely to contribute to the mutation load reported to occur in human tumors.
Other processes, such as inflammation, oxygen radical damage accompanying tissue injury, and a flux of macrophages may contribute to the mutation frequency (Harris et al, 1978).
Y-family polymerases may contribute to the mutations induced by M1dG in vivo.
Taken together, the findings provide key insights into the mechanism by which kataegis arises, and identify two proteins likely to contribute to the mutations seen in breast cancer.
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