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This result is consistent with a greater toxicity of ultrafine particles compared to accumulation mode particles, although changes in particle surface chemistry during the aging process may have contributed to the diminished toxicity.
We suggest that decreased surfactant activity in ETs from animals that received cSPLUNC1 siRNA also contributed to the diminished effectiveness of the ET mucociliary system since surfactants are known to have a major impact on this function [12].
The developing necrotic cores in these tumors, confirmed by postmortem histological analysis (histology data not shown), presumably contributed to the diminished photon emission at the later time points.
We previously reported that cultured human diploid fibroblasts (HDFs) undergoing replicative senescence showed reduced levels of HuR, which contributed to the diminished expression of cyclin A, cyclin B1, and c-fos in senescent HDFs [ 49], and also showed reduced AUF1 levels, which contributed to elevating p16 abundance, a senescence marker in this cell system [ 50].
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And to venture into even-deeper waters, no one knows how Europe's birthrate might play out globally: whether it will contribute to the diminishing of Western influence and Western values; whether, as Steyn's book title suggests, America will have to go it alone in this regard.
An aging midwifery population also contributes to the diminishing cadre of practicing midwives in Ghana.
For example, the age-dependent increase of the senescence regulators (e.g., p16) contributes to the diminishing of aged NSC pool.
Receptor desensitization and ion channel fatigue are also factors that may contribute to the diminishing response with repeated mechanical loading (Ralevic and Burnstock 1998).
However, the extent to which mentorship (or the lack of robust mentoring relationships) may be contributing to the diminishing interest in academic research careers among young physicians in Japan is not known.
This finding confirms the positive functional role of Thr 44 phosphorylation in the modulation of CK1e activity, and explains how L39Q mutation contributes to the diminishing of CK1e activity in the Wnt/β-catenin pathway.
In the long run, it's sure to contribute to the Diminishing of VCR Dominance.
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