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Allosteric inhibition not only increased the response of unmutated BCR/ABL to Dasatinib but also contributed to overcome resistance of BCR/ABL-T315I in a synergistic manner in all models used.
These findings indicate that other adaptive changes might have happened during the chronic exposure to Fd during selection for Fd resistance, which contributed to overcome cell death despite increased autophagy.
The inclusion of items which are simple (like BMS 1 "Changing position while lying") but also items which are difficult to perform (like BMS 6 "Climbing stairs") could have contributed to overcome any potential ceiling and floor effects.
It was suggested that most of the QTLs were associated with leaf chlorosis and plant survival while some of them affected multiple waterlogging related traits.Such as QTL, Qwt4-1 contoibuted tovercomeme different waterlogging related stress like leaf chlorosis and reduction of plant biomass [ 70].
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PREDICT has also contributed to overcoming the third translational research roadblock: "the gap between knowledge need and discovery".
Such interdiciplinarity has contributed to overcoming the conceptual confusions hindering and unnecessarily compartmentalizing the scientific study of empathy.
This paper explores if a regionalisation of agri-environmental governance may contribute to overcome these criticisms.
Moreover, "concrete definitions" will contribute to "overcome the vagueness of the concept of social entrepreneurship" (Certo and Miller 2008: 267).
The SCS-MS was shown to be a measure that can be used in schools, contributing to overcome the shortage of instruments for use in this context.
Thus, leads to search new drugs of natural products from marine source that could contribute to overcome other treatment strategies of cancer like radiation therapy.
In this sense, a structure generator can contribute to overcome this bottleneck, since it can provide candidate structures for an unknown metabolite.
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CEO of Professional Science Editing for Scientists @ prosciediting.com