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A PCR analysis showed that the recombined allele could be detected in DNA recovered from two positive mutant outgrowths), showing that c-Myc-deficient epithelial cells survived and likely contributed to outgrowth formation.
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Vesicles are known to fuse in growth cones prior to synapse formation, which may contribute to outgrowth.
In this context, the polymorphism of NQO1 gene involved in benzene activation and participating in benzoquinone detoxification and reactivating benzene intermediates, might contribute to outgrowth extrinsic effect in exposed cells [ 20].
In other words, outgrowths were not clonal and Lrp5−/− cells can contribute to outgrowths in the presence of wild type cells (Figure S3).
These epigenetic changes, seen in Tet2 insufficiency-triggered lymphoma, possibly contributed to predated outgrowth of Tfh-like cells and subsequent lymphomagenesis.
In vivo, treatment of MCAo with MSCs increased tPA activity, and this increase likely contributed to the observed neurite outgrowth and synaptic plasticity.
The data show p53 protein was transcriptionally activated and contributed to NGF-mediated neurite outgrowth during differentiation of PC12 cells.
Previous research has revealed that glutamine generated from GS1 2 reactions contributes to the outgrowth of tillers via glutamine-dependent cytokinin synthesis (Ohashi et al. 2017).
Moreover, increased expression of androgen-metabolizing genes within castration-resistant metastases suggests that up-regulated activity of endogenous steroidogenic pathways may contribute to the outgrowth of 'castration-adapted' tumors.
Ndel1 and Vimentin contribute to neurite outgrowth, a read-out for axonal regeneration [20] [22], [24] [26].
The concomitant MSC induced reduction of PAI-1 and increase of tPA in astrocytes of the IBZ thereby amplify tPA activity which contributes to neurite outgrowth.
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