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Growing flies at a higher temperature resulted in higher lethality, indicating that the rt gene also contributed to normal development.
In contrast, the 47 genes differentially acetylated for H4K5 in controls were classified into brain processes such as negative regulation of axogenesis, of neurogenesis, and of cell development, but also contributed to normal brain development and neuronal differentiation (Table 1; Additional file 1: Table S3 and 5).
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Such factors may contribute to normal variation, but they shouldn't be used to explain why a child doesn't meet essential milestones.
To discover the biological mechanisms that contribute to normal social activities, animal models of social behavior have been developed.
This is postulated to contribute to normal human ageing [1] and fibroblasts from WS patients have a much-reduced replicative capacity [3].
In healthy adults, an excess of VEGF in the lung compared to other tissues contributes to normal lung tissue homeostasis and endothelial tropism [30].
Microenvironmental physical properties, such as stiffness and tension, are becoming increasingly acknowledged as contributing to normal cellular processes and to the development of diseases [142 145].
This is postulated to contribute to normal human aging [1] and fibroblasts from WS patients have a much-reduced replicative life span [3].
The current study was designed to address the hypothesis that TGF-β1 and TGF-β2 might contribute to normal reparative response of airway epithelial cells (AECs).
Interactions among these networks contribute to normal variations in cognitive functioning and to the aberrant affective profiles present in certain clinical conditions, such as major depression.
Understanding brain reserve in preclinical stages of neurodegenerative disorders allows determination of which brain regions contribute to normal functioning despite accelerated neuronal loss.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com