For example, phosphorylation and acethylation of c-Myc could affect its protein-DNA and protein-protein interactions, which would contribute to its selective binding of target gene promoters.
Taken together, our results indicate that DMC-induced activation of these paraptosis-associated signals, including proteasome inhibition (possibly leading to the upregulation of CHOP, Noxa and Bim), Alix downregulation and superoxide generation, may contribute to its selective cytotoxicity to breast cancer cells, sparing normal cells.
I was gone by then, but I thought the decision to be selective about ads contributed to its demise.
While templated poly(1,2-diaminobenzene) has already been described as charge selective in the past, electrochemical experiments in this work demonstrate that another mechanism (most likely, size selectivity) also contributes to its ion selective behaviour.
Since amorphization usually occurs on the quartz surface during scratching and indentation [24, 25], it is reasonable to speculate that amorphization during scanning/scratching at the superficial layer might have contributed to the selective etching of the quartz surface.
We cannot rule out the possibility that unmeasured, complex motivational factors may have contributed to the selective response by hospitals to participate in the surveys.
GULO uses molecular O2 as its electron acceptor, resulting in H2O2 production, which may have contributed to selective pressure to lose this enzyme in some animals (Bánhegyi et al., 1996; Mandl et al., 2009).
These data support a hypothesis that natural selection imposed by protein functional constraints has contributed to selective fixation of certain editing sites and maintenance of the editing activity in plant organelles over a period of more than four hundred millions years.
These may have contributed to the strong selective pressure on UCEs that function as regulatory sequences.
