It has been reported that TNF α protects neurons against amyloid- β (A β) toxicity both in vitro and in vivo, but it also contributes to exacerbating neurodegeneration.
Along with the tumor itself, cancer treatment can also contribute to exacerbate the production of proinflammatory cytokines.
Furthermore, this study showed that bi-fuel operation has lower local and regional impact, and according to the MC analysis, statistically, bi-fuel operation does not contribute to exacerbate global trends in GHG emissions when compared with monofuel operation.
In this sense, urban policy that promotes population growth as a means to benefit from the effects of agglomeration leaves the character of a city, including most of its challenges, unresolved, and may, in fact, contribute to exacerbate them.
When threatened, these cells can be either neuroprotective or contribute to exacerbate the excitotoxic stimuli (reviewed in Bringmann and Wiedemann).
Furthermore the impaired function of (Na + K -ATPase contributes to exacerbate the intracellular Na+ and Ca2+ overload [ 31].
Indeed, the sum of risk factors (eg, rapid weight gain, family history, and ethnic group) all contribute to exacerbate the risk of metabolic syndrome in children born SGA.
It was reported that Gao-binge treatment suppressed expression of lipid oxidation genes in Fxr knockout (KO) mice, which may contribute to exacerbated hepatic steatosis.
Another factor that could contribute to exacerbated fatigue and lower intermittent HiVR at altitude is the downregulation of the Na+, K+ ATPase in hypoxia.
