Sentence examples for contributed to disruption from inspiring English sources

Viability of HeLa cells was not affected for the majority of tandem peptides with the exception of 12R and 15R, whose excess cationic charges may have contributed to disruption of membrane integrity and reduction in cell viability (Supporting Information, Figure S1B, S1C).

PLpro-TM reduces the levels of ubiquitinated forms of RIG-I, STING, TRAF3, TBK1, and IRF3, and contributes to disruption of the signaling required for the induction of IFN.

One of the features of acute renal failure as induced by renal ischemia is the loss tubular epithelial cells (TEC) which significantly contributes to disruption of renal function.

Such a fragment may contribute to disruption of tolerance to fractalkine, resulting in an autoimmune response.

These spindles enhance the peroral EPV infection by contributing to disruption of the peritrophic membrane [ 37].

Eliminating DAB2 expression may contribute to disruption of various signalling pathway in NPC.

Rather, it would contribute to disruption of normal APP gene expression that would accompany AD.

24, 25 Ultimately, this contributes to disruption of whole-body insulin sensitivity and impairs glucose homeostasis.

Thus, dysregulation of other components of the p53-mediated pathway in melanoma may also contribute to disruption of apoptosis.

Rather, changes occur in a hierarchy of gene modules which collectively contribute to disruption of essential cellular functions [ 15- 17].

The binding of a RhoGTPase to the N-terminal GTPase binding domain (GBD) contributes to disruption of this autoinhibitory interaction, which results in the activation of the Drf.