Besides menopausal hormonal changes, interactions of genetic and behavioral factors also contribute to clustering of metabolic risk factors [ 12].
Thus, two mechanisms contribute to clustering of TFEB on lysosomes upon Torin 1 treatment: (1) trapping of the mTORC1 TFEB complex in the inactive state and (2) increase of the amount of mTORC1 bound to the lysosomal surface.
We propose the following model: Under normal conditions, native α-Syn would contribute to clustering of synaptic vesicles at the active zone, and thereby assist with the formation of neuronal SNARE complexes by constraining additional synaptic vesicles to be close to the active zone.
The topic network lets users follow and contribute to clusters of links by subject (software, business, Apple, etc).
The key result of this study indicates a significant reduction in the mean number of medium- and small-sized dendritic profiles (diameter less than 2 μm) contributing to clusters in layer 4 of groups 3 dL and 52 dD compared with group 21/31.
Protein profiles that contributed to the clustering of patient groups in only one blood preparation type were also identified (e.g., CA3), which contributed for the clustering between BMD patients and controls in serum but not in plasma (Fig 2C and D).
To determine to what degree tandem duplication contributes to the clustering of testis-specific co-expressed genes, we analyzed cluster distribution after removal of duplicated genes.
It appears that microtubules contribute to the clustering of neurotransmitter receptors as when they are depolymerized with a drug, thus disrupting clustering of GABAA receptors, GABAergic currents in hippocampal neurons are affected.
Using data from one of the largest samples that has ever contributed to a cluster analysis of health behaviours, six clear clusters emerged: smokers, non-screeners, higher risk ex-smokers, lower risk ex-smokers, sedentary non-smokers and active non-smokers.
Prediction and early identification of spatial clusters of measles outbreaks will be critical to achieving measles elimination and HIV infection may contribute to spatial clustering of measles cases in some epidemiological settings.
