Sentence examples for contributed to attenuation from inspiring English sources

To investigate whether TET1 contributed to attenuation of methylation of TFPI2 promoter in H3R117A mutant LoVo cells, TET1 CRISPR/Cas9 KO plasmid was used to inhibit expression of TET1 in H3R117A mutant LoVo cells.

Moreover, suppression of DC migration and maturation by granulocyte-colony stimulating factor contributed to attenuation of cerebral inflammation and reduction of infarct size, exhibiting neuroprotective effects in murine models of tMCAO [ 42].

Lee et al (11) also found that tubular cell apoptosis was prominent in septic kidneys, and inhibition of apoptosis by caspase-3 inhibitor contributed to attenuation of renal dysfunction.

One factor that may have contributed to attenuation of the effect sizes is the fact that vascular and metabolic risk factors were relatively well controlled in the diabetes group (Table 1).

In order to clarify how alteration in PI3K/Akt and Ras/Erk1/2 signaling pathways contributed to attenuation of cellular FN accumulation, we co-transfected a dominant negative (DN -Akt or a constitutively activateDN -Akt cDNA torthe InsR silenced cells.

We choose point source because it is easy to focus and contribute to attenuation measurement.

A total of 51 of the 2014 sequences evaluated, 14 non-SCCmec and 37 SCCmec, were identified as genes of interest.Of the 171 genes less common in complicated infections, 152 are of unknown function and may contribute to attenuation of virulence.

Furthermore, reduced induction of proinflammatory cytokines by both bcr1Δ and als3Δ might also contribute to attenuation.

Thus, downregulation of these genes in the phoP mutant could contribute to attenuation.

Therefore, the reduction in YopE and YopH synthesis observed in the ΔrelA ΔspoT mutant may also contribute to attenuation.

Of the 171 genes less common in complicated infections, 152 are of unknown function and may contribute to attenuation of virulence.