Sentence examples for contributed to altering from inspiring English sources

It has been well demonstrated that ERK1/2 regulates expressions of neurokinin-1 receptors (NK-1) and cyclooxygenase-2 (COX-2) [ 12, 13], two important mediators of inflammatory pain in central nervous system [ 14, 15], and thus contributed to altering sensitivity to pain.

Importantly, we found that Alu-DR2s are accessible to RARs in vivo in two RA-responsive human cell lines, indicating that the expansion of DR2 motifs within Alu elements during the course of primate evolution contributed to altering regulation of gene expression by retinoic acid.

A number of factors contributed to alter this situation in favour of Egypt.

However, during the initial phases of the epidemic the Italian population has been exposed to a massive information campaign on the risks of an emerging influenza pandemic, which can have contributed to alter the perceived risk.

This contributed to alter how the clinicians perceived 30-day mortality from a rejection and critique to a demand for exploring the data.

This being said, additional change in the dynamics of fire management and/or human land use will almost certainly contribute to altering the future global distribution of fire alongside climate, presenting a wildcard in future fire-proneness.

Concerning macrophages, because they express estrogen receptors [59], [60], we speculate that estrogen/receptor interaction may contribute to altering the expression of glycans on the cell surface, thereby converting macrophages into good targets for paracoccin recognition.

Such studies have implicated the existence of genetic modifiers - genes whose natural polymorphic variation contributes to altering the development of Huntington's disease symptoms.

Thus, the sequence alterations of this region may contribute to altered replication or transcription properties [ 4, 5].

At this point, there are insufficient data to determine the extent to which genomic alteration, hetero- and homo-allelic loss, epigenetic alterations (as methylation) and microRNAs contribute to altered GNG7 expression.

Biochemical and genetic studies have characterized molecular determinants contributing to alter Hcy metabolism.