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While cancer cell lines have contributed to a wealth of knowledge in cancer biology, the use of this cell source is increasingly perceived as a major contributing factor to the dismal failure rate of oncology drugs in drug development.
Molecular cloning of the involved genes [24], [25], elucidation of polysaccharide structures [26], use of monoclonal antibodies [27], [28] and synthetic peptides [29] have all contributed to a wealth of evidence that endoparasites take advantage of molecular mimicry to survive in their hosts (see also Table 1).
In fact, a massive expansion of the calpain family occurred by domain shuffling among unicellular eukaryotes and contributed to a wealth of functionally different genes.
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If you are one of the roughly six million telecommuters in the US, take comfort in the knowledge that by rolling out of bed and shuffling to your desk to start your workday, you are contributing to a wealth of environmental savings.
This led to closer investigations of the efficacy of offender rehabilitation programs and has subsequently contributed to an amassing wealth of 'what works' research [ 29], which indicates that treatments targeted towards rehabilitating offenders are effective.
The return of the importance of scarce land, resources, and intellectual property has contributed to a resurgence in wealth accumulation.
This analysis also showed the program contributed to a correlation between wealth and LLIN use that favored the poor.
The truth is, those grim factories in Dongguan and the rest of southern China contributed to a remarkable explosion of wealth.
The most recent law in addressing the issue, in 2007, emphasizes that "first and foremost, it's the press that can contribute to a critical debate" on wealth and the elaborate tax scheme that, along with the country's oil wealth, keeps Norway's extensive — and expensive — welfare system afloat.
Today, the tax code is primarily benefiting wealthier households, those least in need of public subsidies, and it's contributing to a large and growing wealth gap.
While not politically active, they were generous with their new wealth, contributing to a religious academy in Huntington Beach, Calif., and building the Chisick Auditorium for the Jewish Community Center of Orange County.
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