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The surprising finding of our investigation was a high predominance of recurrent mutations in the BRCA1 gene, which contributed to a substantial proportion of hereditary BC and OC cases.
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It generally results in short-term acute impairment and is believed to contribute to a substantial proportion of alcohol-related deaths and injuries.
Likewise, neuropsychiatric disorders such as depression and schizophrenia contribute to a substantial proportion of disability among both younger and older individuals.
Preterm birth (PTB) (<37 weeks of gestation) is a major obstetrical problem, contributing to a substantial proportion of infant morbidity and mortality worldwide.
Apart from affecting mortality rates, violence also contributes to a substantial proportion of the global health care costs.
This study suggests that a minority of persons with any non-medical acute care days contribute to a substantial proportion of total non-medical days in acute hospitals.
A small number of patients with non-medical days waiting for nursing home admission contribute to a substantial proportion of total non-medical days in acute hospitals.
However, when cells are starved and autophagy is induced, then this process contributes to a substantial proportion of long-lived protein degradation.
In 2007, MCV1 coverage in WHO Africa and South East Asia regions was 74% and 73% respectively [ 7] – two regions particularly vulnerable to disease out-breaks and which contribute to a substantial proportion of the global disease burden of measles.
A systematic review study done earlier showed lack of thermal protection contributes to a substantial proportion of neonatal mortality globally mostly as co-morbidity of severe neonatal infection, pre term birth and asphyxia [ 7].
Diabetes and its complications contribute to a substantial proportion of causes of death in high-resource countries, and in many lower-resource regions, diabetes is rapidly increasing in incidence and prevalence.
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