Exact(1)
In particular, Eliopoulos A. G. and colleagues contributed the pathway of CREB, a key regulator of COX-2 transcription [39].
Similar(59)
Enzymatic reactions contributing to the pathways of extracellular ATP synthesis and degradation play a critical role in regulating the concentration of extracellular ATP and its metabolites near purinergic receptors.
In Alzheimer's disease pathway, the apoliprotein E over-presentation also contributed the overall bias of this pathway to diabetic serum.
However, the extent of presystemic elimination might be greater or lower, depending on the contributing pathway of elimination (e.g., CYPs or transporters), which then results in a lower (more likely) or higher peak plasma concentration (Cmax) in this population.
KR contributed to the pathway development efforts and standardisation of pathway data collection and storage.
Although a number of pathways we have identified contain genes implicated in susceptibility to these diseases in previous single SNP based studies, our analysis presents a new perspective on the number of contributing pathways, the number of genes within pathways that interact to determine disease occurrence, and also identifies novel pathways and genes associated with each disease.
We delineated a novel pathway that might contribute the regulation of UV-induced melanogenesis.
PL contributed to the construction of pathway, collection of molecular interaction data and development of the notation scheme.
Many masses corresponding to metabolites within the bile acid biosynthesis pathway contributed to the segregation of disease phenotypes.
Metabolites within a broad range of pathways contributed to the differentiation of healthy from diseased individuals, as well as between disease phenotypes (Fig. 2A, Table 1).
It has been proposed that together with drug-metabolizing enzymes, OCT1 contributes mainly to the detoxification pathway of liver (Zhang et al., 2006).
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