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However, it is at present unclear how this residue contributed so substantially to such a step, because T81 is located on the protein surface and far away from the active site and access tunnels (Figure 2) (Okai et al. [2013]).
What makes Will Munro so extraordinary as an artist and as a person is that he has not only remained true to such a harsh mistress, but that he has also contributed so substantially to the fabric and heft of this often maleficent metropolis.
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We are proud to contribute so substantially to this global movement, as restoration is both in our own self-interest and it benefits the whole world.
They have contributed so much.
have contributed so poorly".
His hostility to Richardson's sexual ethic notwithstanding, Fielding was happy to build, with a calm and smiling sophistication, on the growing respect for the novel to which his antagonist had so substantially contributed.
A closer look at the distribution of sero-positive samples showed that the adult goat population, and more so the females, contributed substantially to the elevated sero-positivity in goats.
Twenty-nine soates so far have found a way to expand Medicaid which has contributed to substantially decreasing the rate of uninsured people in the United States.
In conclusion, by end of 2010 Global Fund-supported programs implemented by countries had contributed substantially to international targets and will continue to do so to 2015.
The IPCC's summary report went so far as to declare that man's actions have contributed "substantially to the observed warming over the last 50 years".
Monoterpenes are present in large quantities in the constitutive CRD oleoresin, so it is possible that newly induced TPS enzymes in this tissue may not have contributed substantially to the accumulated monoterpene composition at the time point measured.
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