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The optimum QSAR model showed that the parameters SsssCHE index, SddCE-index, T_2_Cl_4, and SssNHE-index contributed in the model.
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The position and axial inclination of teeth were considered on the basis of ideal occlusion of Andrews [19], and all the elements contributing in the model were assumed to be homogenous.
DL contributed in the statistical models.
EH contributed in the parameterization of the model, provided biological understanding of the problem, and participated in the manuscript drafting.
FD contributed in the development of models and algorithms, and in the implementation of the methods.
JDW contributed in the development of the models and algorithms and the implementation of the approaches.
XL contributed in the development of the models and algorithms for co-occurrence analysis and generated the respective data.
KK contributed in the development and implementation of models and algorithms.
JL contributed in the development of algorithms and models, the implementation of algorithms, generation of the signature data and drafting of the document.
JL contributed in the development of algorithms and models, the implementation of algorithms, generation of the results and drafting of the document.
No hydrophobic descriptor was found contributing in the final model obtained by the SW algorithm.
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