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The main hypothesis of this paper is that socio-epistemic underpinning may contribute to validate if foresight quality criteria are suitable as a tool for scientific criticism of foresight.
Integration of experimental data from in vitro and in vivo studies with "omic" analyses of human patients affected with cancer, immune diseases, inflammation or neurological disorders will likely contribute to validate the clinical relevance of AhR and the possible benefits of modulating its activity by pharmacologically-driven strategies.
Among these, we found known imprinted genes, such as IPW, GRB10, INPP5F and ZNF597, which contribute to validate the approach.
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Such data would also largely contribute to validating the interest of our mutant population for functional genomics in flax.
In this respect the results contribute to validating its use as an outcome measure beyond the immediate outcome of the consultation.
The current gene selection will contribute to validating the role of monocytes in disease activity, to therapeutic interventions, and may improve the knowledge on the regulation of pathways in activated monocytes in chronic inflammation.
In terms of the clinical relevance of a CRC prognosis and the status of metastasis, understanding the underlying mechanisms of CRC tumorigenesis and metastasis will contribute to validating therapeutic targets and improving clinical applications for treating CRC patients.
Ongoing next-generation sequencing-based investigation of gene expression (including transcription profiling) in Musa pathogen interactions by our group will offer potential for further elucidation of gene expression during plant immune responses, and will contribute to validating annotated gene models in the Musa whole-genome sequencing project.
The potential of CISH as a HER2 status assay for routine practice has been the subject of an international multicentre ring study, to which we have contributed, to validate CISH against the current 'gold standards' [ 22].
Together, our results on Slc11a2 transmembrane topology have not only contributed to validate the structural model obtained by homology threading and modeling but additionally provide a structural framework for structure−function studies in this family of transporters.
Dr. Jack Strominger, the Higgins professor of biochemistry at Harvard, said in an interview on Tuesday that the original Watson-Crick discovery was "really a hypothesis based on little scraps of data," and that the work of Dr. Doty and Dr. Marmur greatly contributed to validating its utility.
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