Sentence examples for contribute to transformation of from inspiring English sources

Therefore, loss of Dnase1 and increased MMP activities are identified as factors that may contribute to transformation of mild mesangial into severe membrano-proliferative lupus nephritis.

The mitogenicity of this receptor is well established, and is well known to contribute to transformation of normal mammary epithelial cells [ 2].

Although the ROS generated due to MnSOD deficiency do not necessarily need to be carcinogenic, they can initiate or participate in reactions that contribute to transformation of cells and to a carcinogenic process.

It is therefore possible that the deletion of the 3' part of early HPV-16 mRNAs occurring during cervical oncogenesis could contribute to transformation of cells through deregulation of the viral oncogene synthesis.

The failure of hematopoietic stem cells (HSCs) to express the correct or fundamental adhesion molecules may contribute to transformation of a normal HSC to leukemic cell and to get arrested at a particular step of their differentiation.

These results demonstrated that transformation of CF was exclusively a biotic process, while abiotic processes contributed to transformation of CT and CFC-11.

The prostatic stroma of Tgfbr2fspKO mice independently contributed to transformation of the adjacent epithelia as well as castrate resistance.

This impaired PRLR turnover, which leads to its stabilization and accumulation, presumably increases the magnitude and duration of PRL signaling and contributes to transformation of human mammary epithelial cells [ 69, 70].

We are catching a glimpse of how just DNA sequencing and computation can contribute to the transformation of oncology from the realm of Intuitive Medicine to Precision Medicine (to borrow from Clay Christensen, again).

The Columbia Women's Leadership Network in Brazil Program selects annual groups of up to 20 mid-senior level professionals with the goal of creating a growing network of women who will contribute to the transformation of public service in Brazil.

Epigenetic events at the early stages of neoplasia may contribute to the transformation of stem cells into cancer cells, and to the facility with which phenotypic switches occur in cancer.