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Different factors may contribute to this regulation.
It is critical that these results not be interpreted to suggest that only these genes contribute to this regulation.
CDC-42 may contribute to this regulation through effects on VPC polarization and apical membrane organization, or through a general effect on endocytic traffic [40], [41], [42].
These observations indicate that the level and availability of CXCL12 for CXCR4 is tightly regulated under normal conditions and the present data indicate that CXCR7, which is widely expressed, may critically contribute to this regulation.
These experiments therefore suggest that the GABABR is important in the mediation of the IPC-regulated stress responses and that the Kenyon cells of the mushroom bodies do not contribute to this regulation.
We furthermore speculated that intestinal epithelial LepRb expression could contribute to this regulation, consistent with its role in the defense against E. histolytica.
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Genetic studies indicated that the CCS52A2 gene functions together with WUSCHEL (WUS) and CLAVATA3 (CLV3) in regulating the development of the shoot meristem, and also contributes to this regulation together with the chromatin remodeling pathway.
The weak agonistic effect of sarafotoxin-S6C and the inhibitory effect of ETBR antagonists, show that ETBR also contributes to this regulation even if the vasopressor response to ET-1 seems to be mainly mediated by ETAR.
Our genetic studies indicate that the CCS52A2 gene functions together with WUS and CLV3 in stem cell regulation, and also contributes to this regulation together with the chromatin remodeling pathway.
There are a number of non-mutually exclusive mechanisms that could contribute to this graded regulation of calcium events.
In the baker's yeast, Saccharomyces cerevisiae, the times at which origins undergo activation, or fire, have been shown to contribute to this temporal regulation (Raghuraman et al. 2001; Yabuki et al. 2002; McCune et al. 2008).
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