Sentence examples for contribute to pathomechanism of from inspiring English sources
The alterations in tryptophan-kynurenine metabolism might contribute to pathomechanism of migraine and depression comorbidity.
Emerging evidence suggests that innate immunity and increased oxidative stress contribute to pathomechanisms in amyotrophic lateral sclerosis (ALS).
Further, RPGR isoforms distinctively determine the subcellular targeting of RPGRIP1α1, with deficits in RPGRORF15 -dependent intracellular localization of RPGRIP1α1 contributing to pathomechanisms shared by etiologically distinct syndromic retinal dystrophies.
Our study uncovers an unexplored mechanism of how Aβ may impact the pathology of AD and the identification of key miRNAs affected by Aβ will allow further analysis of target genes and biological pathways contributing to pathomechanisms in AD.
These studies suggest that functional changes of the thalamus contribute to the pathomechanism of chronic pain.
Our study dissects the complexity of human AD pathology, and addresses the hypothesis that amyloid-β (Aβ) itself, a known causative factor of AD, causes neuronal miRNA deregulation, which could contribute to the pathomechanisms of AD.
These results suggest that structural perturbations reduce efficiency of tRNAIle precursor 3′ end processing and contribute to the molecular pathomechanism of this mutation.
It has been assumed that reactive astrocytes could contribute to the pathomechanisms underlying AD by favoring oxidative neuronal damage (Schubert et al., 2001).
In summary, this first-time visualization of proximal, multifocal fascicular nerve lesions in dPNP may contribute to the understanding of pathomechanisms in dPNP.
Identification of such dynamic protein complexes and their coordinated mechanism of action should contribute to better understanding of the dynamic nature of ciliary function in sensory neurons as well as pathomechanism of associated disorders.
This should not only provide a better understanding of the pathomechanisms of this tumour, but also contribute to the development of better diagnostic tools and improved therapeutic strategies.
