For example, for sufficiently short MT filaments, few MTs from the anterior can reach and contribute to orientations in the posterior half of the oocyte.
The current study also revealed that the two centrosomal proteins, Cnn and Apc1, differentially contribute to centrosome orientation and the centrosome orientation checkpoint.
However, contrast adaptation did reduce the difference in orientation tuning observed between different contrasts, indicating that contrast adaptation does contribute to making orientation tuning less contrast-dependent.
While genes do contribute to sexual orientation, other multiple factors play a greater role, perhaps including the levels of hormones a baby is exposed to in the womb.
Physiologically, mechanical stretch is reported to contribute to the orientation of cardiomyocytes, though the molecular mechanism remains to be elucidated.
We propose that Scribble-dependent nascent cell-cell adhesion clusters between neuroepithelial progenitors contribute to define orientation of their cell division.
In fact, the inhibitory mechanisms contribute to the orientation selectivity [42] [45].
Moreover, electrostatic interactions, such as salt bridges, may contribute to the orientation and stability of the amyloid assembly [35], [36], [15], [37].
Taken together, our data suggest that Dsh acts only in part via Vang and that the activities of both Vang and Dsh may contribute to spindle orientation in dividing SOPs.
SIMs can bind to SUMO in two opposite orientations, and the presence of acidic residues either upstream or downstream of the hydrophobic core has been suggested to contribute to the orientation of binding by forming interactions with basic residues in SUMO [23].
