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In a previous study, an effective in vitro system was developed to understand how single cells suspended in CSF adhere to catheters and contribute to obstruction [ 14].
For a given cell, the MCD may then describe a criterion that determines whether IRBCs may be physically segregated and trapped by the spleen, or contribute to obstruction of capillaries in the microcirculation.
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Processes contributing to obstruction in the small conducting airways include disruption of the epithelial barrier, interference with mucociliary clearance apparatus that results in accumulation of inflammatory mucous exudates in the small airway lumen, infiltration of the airway walls by inflammatory cells, and deposition of connective tissue in the airway wall.
Elevation of PEL implied a spread of CMPI toward the luminal surface, and further investigation suggested that the activation of SPFs, which normally reside in the subperitoneal outer area of the colonic wall, contributes to obstruction of the bowel.
In COPD, remodeling of the small airways and lung parenchyma contributes to obstructions in air flow (Sköld 2010), whereas in asthma, airway obstruction may originate predominantly in the larger airways.
Although TGF- β1 is undoubtedly contributed to obstruction-induced fibrosis, it is normally secreted as a latent procytokine complex that needs activation before signaling through TGF- β receptor and mediating fibrogenic effects [ 18, 20].
If there is an obstruction in the intestines, additional food ingestion will only contribute to further obstruction.
A previous study suggested that differences in HMEF design might contribute to filter obstruction under wet conditions.
If clumps form in vivo, they could contribute to microvascular obstruction.
Residual anaesthesia, trauma, oedema, or pre-existing upper airway pathology may all contribute to airway obstruction.
Inhaled anticoagulants have been used to ameliorate the formation of fibrin casts, which contribute to airway obstruction following inhalation injury.
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CEO of Professional Science Editing for Scientists @ prosciediting.com