Sentence examples for contribute to duplicate from inspiring English sources

Our findings suggest that a combination of factors contribute to duplicate gene persistence following whole genome duplication, but that the total expression level and evenness of expression across tissues and through development before duplication are most important.

In duplicates generated via WGD by allopolyploidization, heterosis from interactions between diverged subgenomes could contribute to duplicate gene longevity without necessitating altered function after duplication [ 22].

Functional diversification and neofunctionalization could contribute to duplicate gene retention.

The long-term maintenance of the duplicates may be attributable to sub-/neo-functionalization of their gene functions [ 8, 42- 44] in general, although advantageous effect of the increase of gene dosage by duplication may also contribute to the duplicate gene persistence [ 45].

The presence of paralogous genes and isoforms from splice variants, and quality of the reference sequences could contribute to the observed duplicate mapping [ 39– 41] and some 454 reads mapping to multiple sites may represent transcribed transposable elements.

The division of the locus into two sub-loci may have provided an opportunity for genes to duplicate and contribute to an expanded function of the Type I IFN.

Duplicated genes contribute to functional innovation, with the redundant duplicate often acquiring new functions that derive from an existing secondary function (Conant and Wolfe 2008).

This is the first genome-wide study to address the question of whether genetic divergence in noncoding sequences might contribute to functional divergence of duplicated genes in the hominin lineage.

However, it is unclear how the genes duplicated in this event were lost or persisted during the diversification of teleosts, and therefore, how many of the duplicated genes contribute to the genetic differences among teleosts.

Epigenetic mechanisms, such as DNA methylation have also been suggested to potentially contribute to the expression divergence of duplicated genes [ 62, 63], where transcriptional silencing has often been associated with DNA methylation in promoter regions [ 64, 65].

In contrast, if duplicates contribute to survival upon gene loss, then this effect should be detectable irrespective of the number of essential and non-essential genes identified (provided that the selection is unbiased).