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To test whether protein dynamics contribute to activity enhancement in the V67L mutation, we have studied the conformations and dynamics of the minimized and engineered intein ΔΔIhh-V67CM and a single V67L mutant, ΔΔIhh-L67CM, by solution NMR.
A mixture of metallic and cationic forms of Pd appear to contribute to activity in the Pd catalysts, whereas metallic Rh particles, which can easily segregate onto the surface of CaTiO3 in Rh-doped CaTiO3 upon aging, are the likely source of catalytic activity in the Rh catalysts.
The kinase superfamily shares a conserved core that contains several invariant amino acids that contribute to activity [6].
Plant-derived factors that contribute to the antimicrobial activity in honey may be influenced by local environmental conditions such as climate, water and nutrient availability [12], and entomological factors may also contribute to activity [39].
These observations begin to map the features of 160 which contribute to activity against the NS2 autoprotease.
Since we know the sequence of the peptide substrate on each spot in the array, we could identify the specific residues that contribute to activity.
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GABA-activated Cl− channels contribute to activity-dependent refinement of neural networks by triggering the so-called giant depolarizing potentials providing developing neurons with a sense of activity essential for neuronal survival and co-regulation of excitatory glutamatergic and (inhibitory) GABAergic synapses.
Importantly, miR-9* regulation of BAF53a has been shown to contribute to activity-dependent dendritic growth (Yoo et al., 2009).
Understanding these is important as patellar tendinopathy may contribute to activity-related knee pain which may impair the functional activities of the knee [ 14].
Early NR2B-containing NMDAR exhibit enhanced Ca2+ influx, and are thought to contribute to activity-dependent remodelling and the development of cortical circuitry [ 30].
miR-9*, encoded by the same miRNA precursor as miR-9, has been postulated to contribute to activity-dependent dendritic growth, although no direct evidence was shown (Yoo et al., 2009).
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