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Because the oxidative consequences of PQ are well established and may contribute adverse effects, lipid peroxidation and 20S proteasome functional activity were also determined.
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This effect would be most pronounced for homozygous MA females, who pass on a full copy of their MA-X chromosomes to their sons, and who may also contribute adverse maternal effects to their offspring.
Disruption of alpha(2 AR expression and function may therefore contribute to adverse effects that have been noted in the offspring of pregnant women treated with terbutaline.
These effects are likely responsible for the maintenance of betaAR activity associated with neurotrophic input during synaptogenesis but may also contribute to adverse effects of betaAR agonists used in preterm labor.
The protein is shed from the cell surface where it circulates to come in contact with serum lipoproteins (Morré and Morré 2006a) and extracellular matrices (Kern et al. 2010) and membranes to potentially significantly contribute to adverse effects of aging on cardiovascular and skin health.
These limitations both impede drug delivery and contribute to adverse effects such as cough or bronchoconstriction.
The metal has also been linked with developmental problems and may contribute to adverse effects on the immune and cardiovascular systems.
Aldosterone may independently contribute to adverse effects, given the observation, that aldosterone release may "escape" an ACE-inhibition or AT1 blockade [ 51].
In utero exposure, via maternal smoking, that is believed to contribute to adverse effects of ETS in children [ 32, 33] is uncommon in China.
Activation of hPXR by BPA may contribute to adverse effects and should be considered in future risk assessment studies of BPA in humans.
In addition, glucocorticoids also affect chondrocyte function, which could contribute to adverse effects on the state of the cartilage matrix [ 3].
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