Sentence examples for contradictory pathways from inspiring English sources

These apparently contradictory pathways may reflect the complexity of the apoptosis process in mouse colon mucosa responded to Salmonella infection.

In the context of these largely externally imposed and contradictory development pathways, clarifying the viewpoints and preferences of local people is important, and may help explain the outcomes of past policies, as well as inform future interventions.

It may seem contradictory that PERK/eIF2 α/ATF4 pathway participated in both ER stress-induced apoptosis and autophagy, but recent studies in selenite-treated leukemia NB4 cells indicated that it was the PERK/eIF2 α/axis axis that itself had modulated the switch between autophagy and apoptosis with the assistance of p38.

In this review we analyze possible reasons for the limited efficacy – including the diverse and sometimes even contradictory effects of active Ras pathways in tumor cells – and propose possible alternative methods of tailoring Ras-pathway inhibitor combinations for cancer therapy.

Because of these contradictory results, how the CD279 pathway signals in SLE remains unknown.

Growth arrest and apoptosis controlled by the DDR pathway may appear contradictory with the ability of the virus to sustain continuous cell proliferation.

47 In colon cancer cells, LGR5 could function as a negative regulator of the Wnt pathway, which is contradictory to findings in intestinal stem cells, suggesting its cellular context-dependent functions.

Overall, the functional study of Slit-Robo pathway in GC seems very contradictory by different research groups and further studies will be performed to elucidate the complex signaling pathway in gastric tumorigenesis (Fig.  1).

With regard to HNE, it is well established that HNE interferes with many signalling pathways, but previous reports appear contradictory in some aspects.

These apparently contradictory results regarding the role of Smad pathway in metastasis prompted us to test whether inhibition of Smad pathway by Smad7 induces invasion and metastasis of colon cancer cells.

Currently the available information concerning the main decomposition pathways is rather scattered, and sometimes contradictory.