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This rationale imposes a contradictory challenge to optimize assay specificity (minimize false positive results) and sensitivity (minimize false negative results).
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WASHINGTON — When Defense Secretary Leon E. Panetta travels across Asia next week, on an arc from Japan and China to New Zealand, he will face two almost contradictory challenges.
Similarly, Adel Abdul Mahdi, a Shiite who is one of Iraq's two Vice-Presidents, said, "Some people might see his flexibility as shifting from one principle to another, but it's the need to confront sometimes contradictory challenges — to survive".
In combination, the economic realities brought about by globalization, and the sustainability goals set by the European Union, translate into contradictory challenges for European cultural landscapes.
It is possible that additional or contradictory challenges would be stressed among stakeholders further down in the health system, and further studies are needed to explore such views to be able to provide a more comprehensive picture of the capacity of the health system.
The first poet often gave obscure or contradictory details, challenging the second to complete the poem intelligibly and inventively.
The available evidence about, her writing, her influence over Mill, and even her intellect and personality may be too sparse and too contradictory for this challenge to be surmountable.
Some authors have suggested that GPR30 functions as a membranous estrogen receptor along with ERα and/or ERβ to elicit physiological estrogenic responses in the targeted cells (12, 14), but contradictory data have challenged this idea (4, 15- 17).
The Russian logic of propping up a regime that actually fuels, rather than reduces, violent Islamic militancy can be challenged as contradictory.
Made up of frequently challenging, occasionally contradictory installations, the group exhibition has an ambitious goal: to inspire a "mind-shift" – a re-evaluation of our relationship to the planet and our fellow inhabitants.
I'm coming to this a bit late, but I see that there's now extensive evidence that facts not only don't win arguments, they make people on the wrong side dig in even deeper: "When your deepest convictions are challenged by contradictory evidence, your beliefs get stronger".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com