The other is to prolong a person's life; however, this is only achieved when all three main coronary arteries are severely obstructed and when the contractility of the left ventricle has been impaired somewhat.
The use of digitalis, ouabain, and strophanthin glycosides to slow the rate and strengthen the contractility of the failing heart is one of the most important methods of treatment of this condition.
The free-calcium concentration in this pool must be kept within fairly narrow limits (50 65 mg per litre of extracellular fluid) to maintain the constant internal environment necessary for neuromuscular irritability, blood clotting, muscle contractility, and cardiac function.
During pregnancy the stomach muscles lose some of their tone and become more flabby, and the contractility of the stomach is reduced.
Influences within the heart muscle itself also may increase the demand for blood flow above the level available, making the myocardium vulnerable to alterations in function, contractility, and the maintenance of normal rhythm.
Administered intravenously in moderate doses, dobutamine will increase contractility without affecting blood pressure or heart rate.
Since calcium entry is essential for initiating the contraction of heart muscle cells, calcium channel blockers tend to impair muscle contractility.
Actin is found in the core of the microvillus, and myosin is found in the brush border; because contractility is a function of these proteins, the microvilli have motor activity that presumably initiates the stirring and mixing actions within the lumen of the small intestine.
With this dilation of the kidney pelvis and the ureters there is also a loss of tonicity or contractility in the pelvis of the kidney and the ureters.
Since it is the contractility of peristalsis within the ureter that propels urine downward from the kidney into the bladder, stasis of urine in the ureter is accentuated during the pregnancy.
Cardiac contractility and heart rate decrease as a result of hypothyroidism.
