The globulin fraction contains myosin, the contractile protein, which also occurs in blood platelets, small bodies found in blood.
As in striated muscle, smooth muscle contraction results from the cyclic interaction of the contractile protein myosin (i.e., the myosin cross bridge) with the contractile protein actin.
In the heart, numerous examples of contractile protein changes correlate with functional alterations, both during normal development and during the development of numerous pathologies.
Despite higher proliferation of SMCs under dynamic condition, cells preserved nearly spindle like morphology and contractile protein expression likely thanks to composition of the scaffold.
Prominent uroplakin and contractile protein expression (α-actin, calponin, and SM22α) was evident by immunohistochemical analysis demonstrating maturation of the reconstituted bladder wall compartments.
The distribution, proliferation and contractile protein expression of hCASMCs in the scaffold were then analyzed and compared to those grown under static conditions.
Half of cases are believed to be hereditary, and mutations in cardiac sarcomeric contractile protein genes have been reported with autosomal dominant inheritance.
This study was designed to evaluate whether in vivo caspase inhibition can prevent myocardial contractile protein degradation, improve myocardial function, and attenuate ventricular remodeling.
This highly conserved contractile protein likely drives cell-sheet movements throughout phylogeny.
(B, C) Representative immunoblot images and a quantitative summary for relative contractile protein expression (n = 4).
Figure 1 Gross morphology and contractile protein expression in the rabbit mesenteric artery.
