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Cellular structures gradually become organized during muscle development to raise a mature contractile cell.
This is a conservative comparison to the types of displacements that could occur in the stroma given that the most contractile cell type found there, the myofibroblasts, produce considerably more force than a MEF [28], [29].
SRF is recognized as a vital factor for normal cytoskeletal and contractile cell activities and all the module 29 genes (MYH11, CNN1, ACTG2, MYLK) are known to be direct targets of SRF [21].
Morphological and lineage marker assessment indicates that MSCs, even within shallow durotactic gradients, migrate to stiffer matrix and then differentiate into a more contractile cell, though this behavior is complicated by some degree of 'memory' of the previously soft environment from which they migrated.
With increasing substrate elasticities contractile cell forces rose.
Myofibroblasts are a contractile cell types with actin expression (Hinz et al, 2001).
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This shows that cells with reduced actomyosin contractility act as passive force transducers between other contractile cells in a cluster, consistent with the force scrambling mechanism.
Contractility rate was enumerated from a 30 sec count of the synchronously contractile cells in three random fields.
Muscle tissue is composed of contractile cells or fibers.
I. Stiffness and prestress are closely associated in adherent contractile cells.
Unregulated activity of myofibroblasts, highly contractile cells that deposit abundant extracellular matrix (ECM), leads to fibrosis.
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