Sentence examples for continuum progression from inspiring English sources

However, as gastric dysplasia belongs to part of a widely accepted multistep, continuum progression cascade from normal gastric tissue to adenocarcinoma (Correa, 1988), it implies vague molecular distinction of gastric dysplasia that may render characterisation and discrimination tougher for Raman spectral analysis.

After visual inspection for a distinct gap in the continuum, disease progression groups were determined.

This hypothesis is based on ovarian tumours showing a continuum of progression from serous borderline tumours to serous cystadenocarcinomas.

Actinic keratosis is associated with epidermal atypia and is thought to represent a continuum of progression from dysplastic keratinocytes to cSCC.

Intervention studies can be placed on a continuum, with a progression from efficacy trials to effectiveness trials.

They share lineage with the corresponding benign cystic neoplasm, often through an intermediate (borderline tumour) step, supporting the morphologic continuum of tumour progression.

These mutations exhibit the continuum of tumour progression between benign cystic neoplasms and the corresponding carcinomas such as endometrioid, clear cell and low-grade serous carcinomas, often through precursor lesions such as ES and borderline tumours (Cho and Shih, 2009).

Growing numbers of genetic alterations are also associated with an increasing growth fraction (>10 %) However, this suggests a continuum in the progression of these tumours and is hardly helpful in the assessment of individual cases.

Identical mutational profiles were observed in different areas from benign to borderline and malignant components of the same tumors in 12 of 15 cases, thereby supporting the morphologic continuum of tumor progression in mucinous ovarian tumors [17].

These latter studies highlight the imperfect nature of the current histological grading system and, importantly, support the view that low and high grade tumors reflect distinct pathobiological entities rather than a direct continuum of cancer progression, and that intermediate grade tumors likely arise from these two distinct pathways [ 20].

Advanced prostate cancer comprises a series of states along a continuum of disease progression depending on whether serum androgen levels are in the castrate range or not, and whether clinical metastases are present versus only a rising prostate-specific antigen (PSA).