Sentence examples for continuum of effects from inspiring English sources

These data demonstrate that effects which may seem discrete with the chosen threshold in fact reflect a continuum of effects over a larger region.

This work also highlights the similarities between age differences in healthy older versus younger adults and differences between adults with mild cognitive impairment and controls, suggesting a continuum of effects due to age and neuropathological brain changes.

The regression models we built showed that, in many cases, there is a continuum of effects influencing the molecular state of a target pathway and that, in specific pathways, (i.e. Gap junction and ErbB signalling pathways) toxicity is observed either above or below a given threshold of pathway activity (Figure 5).

Only if all of these mechanisms fail will there be hypothyroidism, the first adverse effect in the continuum of effects resulting from perchlorate ingestion.

Therefore, HR is viewed as part of a continuum of effects mediated by defense elicitors [ 4, 5, 15, 25, 27– 29].

Within this framework structural factors (which include physical infrastructure and the wealth of a society, through to the political and policy environment) can be seen to create a continuum of effects which may enhance or diminish the health of populations.

These findings appear plausible because it is likely that a drug focused on improving the pathophysiology of sepsis will have a continuum of effect on patients, potentially anchored at one end by improvements at a cellular level, but presumably then acting to improve individual organ or multiorgan function, and hopefully leading to a reduction in death rate.

This data-driven conclusion buttresses the theoretical continuum of effect: for many outcomes, such as HIV acquisition, pregnancy or intimate partner violence, there is no conceptual basis for age disparities of 4 years having no impact at all on the outcomes but for age disparities of 6 years substantially determining outcomes.

Fetal alcohol spectrum disorders (FASD) describe the continuum of phenotypic effects that may result from prenatal alcohol exposure (PAE).

More continuous measures of ADHD symptoms or of specific underlying neurobehavioral domains may be the most powerful way to detect lead and tobacco effects, because ADHD may represent the tail of a continuum of behavioral effects produced by environmental chemical exposures and other etiologic factors (Mercugliano 1999).

Although the BPb levels of U.S. populations have dropped markedly compared to 30 years ago, new concerns have been raised regarding possible adverse health effects in children at BPb levels < 10 μg/dL; perhaps there is no safe threshold but, rather, a continuum of toxic effects (Canfield et al. 2003).