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For cells to survive under a chronic ER stress condition like prolonged hyperglycemia, they must have a mechanism by which ER stress can be continuously tolerated.
A range of DSS doses were initially investigated to determine the maximum non-lethal dose that could be continuously tolerated by larvae at 3 days postfertilization (dpf).
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Although the patients were continuously encouraged to tolerate the highest possible current, it is possible that real-time information with visual feedback on the electrically induced force production would have encouraged and motivated the patients to tolerate higher current amplitude, thereby improving the effectiveness of the NMES treatment.
In malaria prophylaxis, a 30 mg daily dose of primaquine has been shown to be well tolerated even when given continuously for as long as 20 weeks.
CPET was performed using standardized protocol [ 31]; work rate was continuously increased by 5 – 15 W/min to a maximum tolerated level on an electromagnetically braked cycle ergometer (ViaSprint 150 p, Ergoline, Germany).
Flow, airway and esophageal pressures were continuously recorded during 10 min under PSV with the minimal tolerated PSL, and then under PAV + with the gain adjusted to target a muscle pressure between 5 and 10 cm H2O.
Corruption no longer tolerated.
Dissent is not tolerated.
Why is it tolerated?
L.B.J. grimly tolerated George Ball.
will not be tolerated.
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