In theory, anti-HIV gene-modified hematopoietic stem cells can continuously provide HIV-resistant immune cells throughout the life of a patient.
To demonstrate that resistance phenotypes resulted from chromosomal mutations, we continuously sub-cultured resistant strains for 10 generations without H2O2 treatment.
A unified national smart grid would form the entire skeleton of a modern electricity system, allowing us to efficiently carry large amounts of electricity over long distances in a network that is integrated, continuously monitored, and resistant to failure.
The beet sugar industry continuously seeks CLS-resistant sugar beet cultivars as one strategy to combat this disease.
In the 1950's, manufacturers targeting this new wave of consumers became household names; Pyrex, the continuously improving shock-resistant glass, was ubiquitous by the 1940's and 50's, Moderne carafes kept coffee hot at the table, and "casserole dishes," encouraging oven-to-table service for buffet-style dinners, became the norm.
The pharmaceutical industries and healthcare systems of the world are continuously fighting multidrug-resistant strains of bacteria the last 50 years.
Of note, wtMUTZ3 cells were found to lack the expression of hTERT mRNA (Fig. 1a), which might have contributed to the failure to generate a continuously proliferating, doxorubicin-resistant cell population.
For these reasons, this study addressed the transcription analysis of hENT1, dCK, RRM1, and RRM2 in parental cell lines and in isolated variable resistant subclones continuously exposed to gemcitabine to determine possible predictive markers for gemcitabine resistance.
All hospitals are obliged to collect and analyse continuously nosocomial infections and resistant pathogens.
These data suggest that the phenomenon of extensive and continuously increasing transmission of resistant strains followed by their disappearance from blood (while remaining in reservoir) is not as widespread as previously foreseen.
