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Patients included in the study were 18 years or older, diagnosed with renal disease for at least 12 months, and continuously enrolled with the insurer for at least 24 months between September 2002 and November 2005.
Patients were required to be continuously enrolled with the health plan in the same calendar year and have no other type of interstitial lung disease (ILD) diagnosis after their last IPF claim in that calendar year.
Patients had to be continuously enrolled (with no more than 45 days of disenrollment) in HVMA and insured with Harvard Pilgrim Health Care (HPHC) for at least one year prior to and one year after the first prescription of oral antidiabetic medication.
A nested case control study was conducted in a privately insured population in a single Midwestern state including a total of 184,480 patients aged 18 years or older who were continuously enrolled with the insurer for at least 24 months between September 2002 and November 2005.
In order to determine the incidence of diabetes, we defined in a next step a retrospective cohort (2006 2011) which included adult persons who were continuously enrolled with Helsana Group during the 6-year period, from January 1, 2006, until December 31 , 2011
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Patients with missing demographic or enrolment values, an invalid day's supply, not continuously enrolled or with a previous claim for pancreatitis (chronic or acute) during the baseline period were excluded.
A surprising finding of the present study is that the proportion of continuously enrolled patients with at least 1 DMD claim remained constant at about 53%-54 53%-542006 to 2011.
Of the 111,333 persons who were aged 25 79, continuously enrolled at Group Health, with at least one visit in the prior 2 years, we excluded 46.5%% because of prevalent CVD or other significant disease, or with filled prescriptions for HMG-CoA reductase inhibitors or isotretinoin.
Patients were continuously enrolled in the study with five patients a day, respectively.
Of continuously enrolled patients, the proportions with at least 1 DMD claim were 54% (n = 8,248) in 2006 and 53% (n = 8,451) in 2011.
The primary outcome measure is the proportion of women continuously enrolled for 24 months with ≥1 mammogram in the past 24 months.
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