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Histological assays revealed that hMSCs continuously differentiated into chondrogenic cells and osteogenic cells after 2 week incubation in PLGA nanofibers.
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One possible explanation is that siphonophores have continuously developing differentiated zooids [ 24].
A number of studies have shown that adult stem cells in different tissues have important roles in tissue homeostasis, such as spermatogonial stem cells continuously producing differentiated progeny in testis.
It has been reported that in European sea bass that has GSD + TE, the expression level of dmrt1 mRNA increased continuously in differentiating and differentiated testes between 150 and 300 DPH, while in adult ovaries it increased until 200 DPH and then decreased to an undetectable level [ 86], which means that dmrt1 is not necessary for ovarian maintenance in this fish species.
The epidermis is continuously regenerated by terminally differentiated keratinocytes that migrate from the inner basal layer (proliferative compartment) to the outer cornified layer (terminal differentiated compartment): this process is known as cornification, or formation of the cornified envelope.
This is probably most apparent in the skin where c-Myc upregulation is associated with the transition from slow-dividing keratinocyte stem cells to highly proliferative transit-amplifier cells, whose multiplication is needed to meet the requirements of an organ that is continuously sloughing off terminally differentiated cells [38].
This type of drug allows a stable population of cancer stem cells to remain and continuously repopulate the progenitor and differentiated cells.
In the Drosophila ovary, two or three GSCs at the tip of the germarium, the most anterior region of the Drosophila ovary, continuously self-renew and generate differentiated GSC daughters, cystoblasts (CBs).
c Mucinous, partly well-differentiated, adenocarcinoma was continuously from the base of the diverticulum.
Adult stem cells continuously undergo self-renewal and generate differentiated cells.
Most current vaccines act by inducing long-lived plasma cells - terminally differentiated B cells - that continuously secrete antibody over a considerable period of time [ 5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com