Exact(5)
All these virulence properties designate AIEC as a possible pathogen potentially able to induce persistent intestinal inflammation, by crossing and breaching the intestinal barrier, moving to deep tissues, and continuously activating macrophages.
Their virulence properties designate AIEC as a possible pathogen potentially able to induce persistent intestinal inflammation, by crossing and breaching the intestinal barrier, moving to deep tissues, promoting granulomas, continuously activating macrophages and producing inflammatory responses [14] [18].
Vagus nerve stimulation prevents seizures by continuously activating noradrenergic projections from the brainstem to the cortex.
We hypothesize that the viral integrations may block the repression of these genes by continuously activating the transcription or inhibiting the binding of repressor molecules.
This is because, for hepatitis C, inflammation is a contributing factor for carcinogenesis as compared to hepatitis B. It has been reported that HCV core results in carcinogenesis at a high rate by continuously activating PPAR α [ 24].
Similar(55)
In the final part, a conceptual framework is discussed that shows that a major purpose of increased SNS activity is nourishment of a continuously activated immune system at a systemic level using energy-rich fuels (glucose, amino acids, lipids), while uncoupling from central nervous regulation occurs at sites of inflammation by repulsion of sympathetic fibers and local adrenoceptor regulation.
As a consequence, the receptor is continuously activated, leading to uncontrolled growth and activation of mast cells (Fig. 1) [ 2].
Immobilized AeHGF-Fc continuously activated Akt in HepG2 cells whereas Akt activation induced by soluble HGF rapidly decreased with time, indicating that immobilized AeHGF-Fc follows different signal transduction pathways compared to soluble HGF.
Caspase-3 cleaves the kinase to yield a 41-kDa catalytically active fragment and a 37-kDa regulatory fragment, which continuously activate the kinase.
The results showed that AMPK was continuously activated in the differentiation process (Fig. 4c, d).
When the cell's store of NADPH is above a certain threshold, the molecule continuously activates an enzyme called CaM kinase-2, which in turn keeps caspase-2 switched off.
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