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However, Villani is quick to add that those who spent too much on the lavish excesses of continuous remodelling and refurnishing of homes were sinners and could be "considered crazy because of their extravagant spending".
Bone is a highly dynamic tissue undergoing continuous remodelling, with a fine equilibrium between bone formation by osteoblasts and resorption by osteoclasts (OCs) [10].
Similar to cartilage, the bone tissue undergoes continuous remodelling.
These observations suggest that some regions of T84 tight junctions may be under continuous remodelling.
However, it is generally hypothesised that continuous remodelling of the graft occurs with the transplant becoming more like hyaline cartilage.
Bone metabolism is a continuous remodelling process involving both bone formation by osteoblasts and bone resorption by osteoclasts.
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To withstand the applied functional load, continuous remodeling is conducted to reach a "steady state".
In contrast to artificial biomaterials, natural ECM has the advantage of undergoing continuous remodeling which allows adaptation to diverse conditions.
The biological sequence of repairing the replaced lamina and spinous process was characterized by slowly progressive creeping substitution, with continuous remodeling.
Bone is a living tissue undergoing a continuous remodeling, in order to respond to a variety of different stimuli, ranging from mechanical loading, to hormonal factors and calcium homeostasis.
Bone is not an inert structure but a living and metabolic active tissue, which undergoes continuous remodeling throughout life, to allow bone architecture to respond to mechanical stress, consisting in bone tissue renewal to replace old bone tissue with new bone matrix.
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