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Chronic cardiac failure is a result of previous or continuous insult against the heart, such as ischaemia, valvular pathologies or genetic abnormalities.
Non-genetic factors of tumor microenvironment/paracrine milieu have been shown to integrate and influence the genetic framework of cancer; therefore we asked if continuous insult from OPG rich microenvironment could drive normal mammary epithelial cells (HMEC) towards tumorigenic.
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To supplement its own antioxidant arsenal and manage continuous insults, skin care requires multi-disciplinary approaches (e.g., nutraceutics, chemotherapeutics, cosmeceutics, and esthetics).
These continuous insults could result in a chronic low level of inflammation associated with insulin resistance.
Hemodialysis patients are exposed to continuous pulmonary insults of multifactorial origin, such as hormonal and metabolic derangement associated with end-stage terminal disease, which may induce pulmonary vascular alterations and consequent increased resistance.
Immune system homeostasis is challenged by continuous external insults, such as saturated fatty acid rich diets (8), pathogen-associated molecular patterns like lipopolysaccharide (LPS) (9), advanced glycation end products (AGEs) (10), burden of infection (11), and oxidative stress (12).
A color-coded contour plot was made for the association between good outcome and the number of secondary insults of ICP during the ICU stay, as defined by continuous values of insult duration and thresholds.
Two from the mob got in the front seat of the ambulance and spewed a continuous flow of insults as we drove about a mile, to where an Army commander, a lieutenant colonel, was stationed.
They published full-page ads in Italy's two leading national newspapers and The International Herald Tribune, objecting to "continuous slander and insults" by the media, prosecutors and Italian tax authorities.
It may be that Trump's continuous stream of insults and oddities — say, going off on South Korea when North Korea detonates a bomb — is not clinical but tactical, a high-level version of the distracting patter perfected by the three-card monte guys who used to work their swindles on the street corners around midtown Manhattan.
I didn't see Ed Gillespie out on the road emitting a continuous stream of personal insults that, although spoken aloud, sounded somehow misspelled, but I did miss the debate, so it is possible that it happened.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com