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The device, made by Medtronic MiniMed, is called the Paradigm Real-Time, a combination insulin pump and continuous glucose sensor.
A major advancement in the future will be the development of a continuous glucose sensor to treat diabetes.
Development of an artificial pancreas would allow to restore control of blood glucose by coupling an infusion pump to a continuous glucose sensor in the blood.
Increased continuous glucose sensor use also shows A1C reduction.
Bruce Buckingham (Stanford, CA) discussed approaches to "closing the loop" with CSII, a continuous glucose sensor, and a control program.
The first goal for developing a reliable in vivo continuous glucose sensor is to detect unsuspected hypoglycemia.
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Continuous glucose sensors based upon polyampholytic smart hydrogels (PSHs) have been intensively studied for biomedical and bioprocess applications.
We report here on the marriage of minimally invasive, continuous glucose sensors and a direct electron transfer type glucose dehydrogenase enzymatic system.
Simulations are carried out by properly addressing the available technological limits and the unavoidable uncertainties in real-time continuous glucose sensors as well as possible malfunctioning on the insulin delivery devices.
Early studies demonstrated the feasibility of automated insulin modulation using subcutaneous insulin pumps and continuous glucose sensors (1– 3).
In patients unable to recognize hypoglycemia symptoms, frequent home monitoring or use of continuous glucose sensors are critical.
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