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The discrete mechanics does not contain any continuous differentiation, but contains only difference quotients.
Integrity of the osseous tissue requires the contribution of mesenchymal stem cells and their continuous differentiation into an osteoblastic phenotype.
Taken together, these data represent an original investigation of continuous differentiation of hMSCs into chondrogenic and osteogenic cells in PLGA nanofiber scaffold.
Long-term stability of arthroplasty prosthesis depends on the integration between the bone tissue and the implanted biomaterials, which requires the contribution of osteoblastic precursors and their continuous differentiation into the osteoblastic phenotype.
The epidermis is the thinnest of the three layers, but mitotically is the most active layer due to the continuous differentiation of keratinocytes into the cornified epithelium, which is exposed to the environment.
However, isolating and purifying CSCs are sometimes challenging because of their scarcity and continuous differentiation.
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He postulated that reality is a self-unfolding of dynamic structures or templates ("Begriffe"); as the external contrasts of these templates arise, they are reflected in a continuous internal differentiation inherent to the templates, thus creating further external contrasts, with the result of an increasingly interrelated web of dynamic dependencies.
We show that LTB4 autocrine activity also provides for continuous osteoclast differentiation via BLT1/BLT2 receptors on macrophages due to PLA2 activation.
Supporting this hypothesis, a developmental timing assay, making use of the different maturation times for green fluorescent protein and red fluorescent protein, demonstrated that during mid- to late somite stages there is continuous cardiogenic differentiation in the ALPM.
In physiologic conditions, this may function not only to recruit neutrophils to joint spaces and exacerbate the inflammatory conditions but also to act as a complementary secondary pathway for continuous osteoclast differentiation leading to bone loss.
To account for the specific observations made for this system in East Asia (i.e. a continuous genetic differentiation along the latitude shaped by two groups of lineages and alleles showing clinal distributions, and a significant decrease of genetic diversity from north to south), a third scenario, named the Overlapping model, has recently been proposed (Fig. 1).
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