Exact(3)
This fact results in a continuous degeneration and dysfunction of articular soft tissues.
Satellite cell deficiencies could arise because of the excessive demands on repair mechanisms necessitated by the continuous degeneration of unstable muscle that does not express dystrophin.
X-ray analyses at two time points indicated that a continuous degeneration of initially normal appearing bone tissue (claviculae, humeri) occurred.
Similar(57)
Furthermore, analysis of muscle fibers provides evidence of continuous muscle degeneration and regeneration.
We further speculate that continuous muscle degeneration of dystrophic muscles may lead to progressive injury of muscle fibers and vessels with consequent depletion of these myo/endothelial circulating progenitor cells.
Torke, who moved to the East Side 20 years ago and has been a constant activist for its renewal, has seen the story play out in a continuous loop of degeneration and futility.
In mdx mice, muscle pathology starts at two weeks of age and is characterized by a continuous cycle of degeneration and regeneration of skeletal muscle cells that peaks between three and four weeks of age.
This observation could mean that TGAs follow a continuous process of degeneration.
Loss of dystrophin results in sarcolemmal instability, which causes the muscle to undergo continuous cycles of degeneration and regeneration.
One of the pathogenic events associated with DMD is the continuous cycle of degeneration and regeneration (4).
Another pathogenic event associated with DMD is the exhaustion of satellite cells that replace damaged fibers, due to a continuous process of degeneration and regeneration.
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