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At this time we are unable to say if this cell line will continue indefinitely to proliferate as a continuous cell line but schistosomal livers seem to be a good source of epithelial cells that can be isolated using the method described here.
Pfragner, R. et al. Establishment of a continuous cell line from a human carcinoid of the small intestine (KRJ-I).
Cytopathic effect and plaque formation by Arboviruses in a continuous cell line (XTC-2) from the toad Xenopus laevis.
McFall RC, Sery TW, Makadon M. Characterization of a new continuous cell line derived from a human retinoblastoma.
D341 Med is a new continuous cell line and transplantable xenograft derived from a cerebellar medulloblastoma.
A new continuous cell line and transplantable xenograft, D283 Med, was derived from the peritoneal implant and ascitic fluid of a child with metastatic medulloblastoma and grew in vitro in suspension culture with spontaneous macroscopic spheroid formation.
Similar(25)
In vitro systems such as primary cells and continuous cell lines are gaining momentum in ecotoxicological studies.
Adaptation of continuous cell lines to growth in suspension in a chemically defined medium has significant advantages for design and optimization in manufacturing of biologicals.
Current regulations and recommendations proposed for the production of vaccines in continuous cell lines of any origin demand that these be free of exogenous viruses, particularly retroviruses.
Continuous cell lines (CCLs) engage in 'wasteful' glucose and glutamine metabolism that leads to accumulation of inhibitory byproducts, primarily lactate and ammonium.
Residual host cellular DNA (rcDNA) is one of the principal risk associated with continuous cell lines derived medicines such as viral vaccines.
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