HIV-1 Tat protein continues to be implicated in the pathogenesis of HAND, in part, because there is significant neuronal dysfunction even though neurons are not infected by HIV-1 virus (Nuovo et al., 1994; Merino et al., 2011).
Among the viral products, HIV-1 Tat (transactivator of transcription) protein has been shown to be neuroexcitatory and neurotoxic, and it continues to be implicated as a causative agent in HAND (Sabatier et al., 1991; Weeks et al., 1995; Haughey et al., 1999; Nath et al., 2000; Perez et al., 2001; King et al., 2006; Buscemi et al., 2007b; Agrawal et al., 2012).
Whether it's disgraceful labour practices, disregard for local communities or dealings with offshore detention centres, Australian businesses continue to be implicated in severe abuses that contravene international human rights law.
Healthcare providers nationwide are still not getting the message as fentanyl patches continue to be implicated in scores of deaths.
Companies based in British Crown Dependencies will continue to be implicated in money laundering by human trafficking gangs, weapons dealing and the large-scale theft of essential revenues from poorer countries.
Armed confrontations between criminal groups and the armed forces are common, and the army and police continue to be implicated in human rights violations such as extra-judicial killings, enforced disappearances and torture.
While doctors, the majority of whom were men, continued to be implicated in abortion offences following the Bourne ruling, it was ordinary lay women practitioners who were overwhelmingly tried and convicted as abortionists and were the target of the fiercest criticism and public vilification.
Despite these improvements, ground beef continues to be frequently implicated in E. coli O157 outbreaks.
CASP6 has been implicated in the early pathogenesis of Alzheimer's disease and continues to be an active participant in the later stages of the disease [ 52, 53].
That is one of the interview's defining moments: El Shazly's unwillingness to be implicated in the usual interrogation, or to continue with the line of inquiry the security forces started and accept their questions as the right ones.
