Exact(1)
However, as hormone treatment continues, adaptive upregulation of growth factor mediated signaling, such as the PI3K/Akt/mTOR pathway, reinforces cross-talks leading to constitutive activation of the cell growth pathways, rendering the patients resistant to hormone treatment [35, 44 47].
Similar(58)
Continuing adaptive evolution will then require new mutations – or intragenic recombination in bacteria.
Finally, the AIAI process by no means precludes either continued adaptive evolution in the new range (e.g., Blair and Wolfe 2004) or a role for hybridization and outcrossing in the new range (Kolbe et al. 2004; Lavergne and Molofsky 2007; Facon et al. 2008).
Subsequent work by Mekel-Bobrov et al. (2005) and Evans et al. (2005) produced such evidence for continuing adaptive evolution of both microcephalin and another microcephaly gene, ASPM (Abnormal Spindle-like, Microcephaly-associated), with both an ancestral form and a new derived form co-existing in human populations.
The heart of continuity theory is the presumption that people are motivated to continue using adaptive strategies they have developed during adulthood to diagnose situations, and adapt to change.
Then, it continues with causal adaptive feedback algorithms to accommodate time-varying sampling intervals.
Figure 3 shows that our adaptive approach continues to provide effective recommendations to non-malicious peers during the attack.
If cardiac overload continues, a transition from adaptive to maladaptive hypertrophy takes place.
Yet the concept of adaptive management continues to evolve, and its record of success remains limited.
Moreover, the studies performed on the D. melanogaster complex have mainly focused on posterior lobe shape even though its link with reproductive isolation and adaptive evolution continues to be debated.
The same set of responses is invariably elicited by the same set of stimuli, because those responses were, and continue to be, adaptive.
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