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The overall median survival is less than 20 months and may be less than 10 months in patients with locally advanced disease and less than 6 months when metastatic disease is present.115 Despite continued efforts to optimize conventional treatment regimens, most patients with pancreatic cancer experience local recurrence or metastatic spread.
However, continued efforts to optimize care are needed as many children continue to enroll in ART programs at a late stage of disease and thus are not receiving the full benefits of treatment.
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The long-term consequences of postprandial hyperglycemia for patients with type 1 diabetes are unclear, but given the weight of available evidence to date, it appears prudent to continue efforts to optimize advanced insulin pump techniques to achieve physiologic PPG profiles.
WHO's "Global Health Sector Strategy on HIV/AIDS, 2011-2015", endorsed by the World Health Assembly in May 2011 highlights the importance of continuing efforts to optimize HIV treatment and "combination" prevention - the use of a range of different approaches to reduce people's risk of infection.
However, continued efforts to improve consistency were considered worthwhile.
The discovery of a new series of compounds that are potent, selective 5-HT2C receptor agonists is described herein as we continue our efforts to optimize the 2-phenylcyclopropylmethylamine scaffold.
Strategies to prevent AKI and its consequences with targeted interventions are sorely needed; however, it will require continued multidisciplinary team efforts to optimize and standardize AKI management to make a difference in this devastating complication.
Individuals who continue to have low CD4 cell counts while on ART should be aggressively evaluated for OIs, and practical efforts to optimize their immunological recovery should be made.
However, efforts to optimize transduction efficiency are still ongoing.
"(1) Undertaking efforts to optimize the rate structure for all requisitioning entities.
Undertaking efforts to optimize the rate structure for all requisitioning entities.
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