Sentence examples for continued activation from inspiring English sources
The increased ratio of RANKL over osteoprotegerin assures generation of osteoclasts from monocyte precursors and continued activation and maintenance of mature osteoclasts; activated osteoclasts erode bone and thus are critically involved in RA pathology.
Moreover, the generation and maintenance of transformed foci requires continued activation of the serotonin receptor.
The septic response may be accelerated following continued activation of neutrophils and macrophages/monocytes [30], which migrate to damaged sites and induce cytokine release.
Thus far, the barriers to generate truly off the-shelf allogeneic cell lines are still quite high, with control of proliferation, continued activation of the cells once they are engrafted, and incorporation of kill switches for safety purposes as critical issues still to be worked out.
Recently we published evidence that continued activation of STAT5 plays a role in the lymphomagenesis of classical Hodgkin Lymphoma [17].
This disruption apparently induces centromere stretching and continued activation of the mitotic checkpoint (also known as the spindle assembly checkpoint) [18], which enables prolonged pre-anaphase arrest, thereby allowing for proper bipolar attachments of sister kinetochores [19].
We developed a multiscale neocortical model proceeding from the molecular to the network level to assess the contributions of calcium regulation of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in providing additional and complementary support of continuing activation in the network.
Parents were then instructed to continue activation at home with two turns per day.
The second expansion phase then began and parents were instructed to continue activation at home with one turn every 3 days.
Our results confirm that the deleterious electrophysiologic changes in area CA1b depend on the continuing activation of N-methyl-D-aspartate receptors.
This implies that the effect of nicotine on diving was due to net stimulation at nicotinic receptors, an effect that is blocked by mecamylamine; and that once invoked, this effect is no longer dependent on continuing activation of nicotinic receptors.
