As metformin was discovered in the era before modern target-based drug discovery, the molecular details of its mechanism of action were not established before it was used clinically and these continue to be an area of vigorous research.
The Mundo Perdido, however, continued to be a centre of vigorous ceremonial activity.
In cases of septicaemic melioidosis, which is associated with a vigorous inflammatory cytokine response [ 9], septic shock continues to be a major cause of morbidity and mortality in patients.
And while, as the Ranking Member, I'll be working on those additional projects you can bet your bottom dollar that as a member of the Communications and Technology subcommittee I will continue to be as vigorous and as vigilant as I've always been in terms of working to make sure that your interests are promoted and that your interests are protected and that your interests are preserved.
The International Monetary Fund echoed that sentiment in its latest assessment of the Chinese economy, published Thursday, noting that "China's near-term growth prospects continue to be vigorous and are increasingly self-sustained, underpinned by structural adjustment".
The dance continued to be vigorous, but by this time "Redemption" had made its basic points and its conclusion was not as striking as its beginning.
The scarlet letter may have little currency left in the realm of sexual indiscretion, but it continues to be put to vigorous use among parents — the shaming impulse particularly thrives in the wealthier precincts of brownstone Brooklyn, where the exacting standards of urbane motherhood would seem to have been invented.
There continues to be vigorous debate about the merits of each of these approaches [ 41], however degassing is not a feasible approach when collecting and processing large numbers of samples in a short period.
Mr. Landesman is expected to be a vigorous and provocative face of the agency.
Belgrade, Smederevo and Veliko Gradište continued to be subjected to more vigorous artillery bombardments, and a number of failed attempts to cross the Danube resulted in heavy Austro-Hungarian losses.
