Karnofsky performance status, dexamethasone use, subsequent treatment evaluations at Duke and bevacizumab continuation were associated with OS.
However, there are other conditions where the grouping of image elements on the basis of connectedness and good continuation is associated with substantial delays (Crundall, Dewhurst, & Underwood, 2008; Jolicoeur, Ullman, & MacKay, 1986 , 1991 Pringle & Egeth, 1988; Roelfsema, Scholte, & Spekreijse, 1999).
Results showed that bevacizumab continuation treatment was associated with a small but clinically significant decrement in Global QoL compared with standard treatment (Stark et al, 2013).
41 Similarly, the use of at least four effective drugs for patients with XDR-TB and three drugs for MDR-TB patients during the continuation phase was associated with the highest odds of treatment success in patients with quinolone-susceptible strains.
Although overall outcome for all patients after bevacizumab progression was poor, continuation of bevacizumab was associated with improved PFS (P<0.0001) and OS (P=0.0138).
Nevertheless, in this unselected group of patients, many of whom had been heavily pretreated, continuation of trastuzumab was associated with a clinically meaningful median TTP of 24 weeks.
10 Continuation of secondary prophylaxis was associated with better outcomes.
We noted that bevacizumab continuation beyond initial progression was associated with modestly improved outcome compared with non-bevacizumab therapy.
One study evaluating the impact of providing a universal postnatal program found that neither a postnatal telephone call nor a postnatal home visit from a public health worker was associated with continuation of breastfeeding to 4 weeks [ 19].
