The adequacy of treatment dose, dosing schedule and oral continuation therapy in our survey is reassuring; the latter was probably due to recent in-service training conducted on the management of uncomplicated malaria at the time of treatment policy change in Uganda in 2006.
Based on the literature survey and biological profile of bis-pyrimidine acetamides summarized in Fig. 2 and in continuation of our efforts in searching novel antimicrobial and anticancer agents [16 18], in the present work, we hereby report the synthesis, antimicrobial and anticancer activities of a series of bis-pyrimidine acetamide derivatives.
In light of above facts and in continuation of our efforts in search of novel antimicrobial and anticancer agents, in the present study, we hereby report the synthesis, antimicrobial, anticancer and molecular docking studies of 2- 1H-benzo[d]imidazol-2-ylthio -N- substituted 4-oxothiazolidin-3-yl) acetamides [2- 1H-benzo[d]imidazol-2-ylthio -N- substituted
In view of these findings, and in continuation to our work in the synthesis of novel anticancer agents [38 42] we undertook the synthesis of bisheterocyclicsulfone compounds analogues for 2-pyridones incorporating biologically active 1,2-dihydropyridine-2-one, chromene, and chromenopyridone in one molecule to explore the promising anticancer compounds.
In view of these facts and in continuation of our interest in the synthesis of a variety of heterocycles of biological importance, we report here an efficient and convenient method for the synthesis of novel nucleobased barbiturates derivatives attached to pyrimidine moiety.
In continuation of our studies in Asian Begonia, these two new species are described and illustrated.
In continuation of our studies in this area, we report the discovery of two attractive new species from southwestern Guangxi: Begonia longgangensis and B. ferox.
In continuation to our interests in the synthesis of pyrazine compounds [21 24] and the enormous applications of pyrazine derivatives in a number of fields prompted us to synthesize new extended iminobenzoates with pyrazine moieties at the terminal positions.
In continuation to our efforts in this drug design paradigm, a library of (E -phenyl- 2-styryl-1H-benzo[d]imidazol-6-yl)mE -phenyl- 2-styryl-1H-benzo[d]imidazol-6-ylnd E -phenyl- 2-styryl-1H-benzo[d]imidazol-6-yl
In continuation of our efforts in this drug design paradigm, a library of (E -phenyl- 2-styryl-1H-benzo[d]imidazol-6-yl)mE -phenyl- 2-styryl-1H-benzo[d]imidazol-6-ylnd E -phenyl- 2-styryl-1H-benzo[d]imidazol-6-yl
